Offline FeNO measurements in accordance to the ATS/ERS guideline

The offline collection kit offers a useful additional option to existing FeNO analyzers, such as the ANALYZER CLD 88 sp. The advantage of offline FeNO measurement is that samples can be easily collected at any location, without the need to have the analyzer at site.

Remote NO collection sites
The offline collection kit allows FeNO testing without the FeNO ANALYZER CLD 88 sp on site. Testing at workplaces, schools, clinics, hospital wards or remote laboratories can easily be conducted.

Efficient use of FeNO ANALYZER CLD 88 sp
The offline collection kit offers a useful addition to an existing FeNO ANALYZER CLD 88 sp and increases efficiency of the workflow. NO samples can be collected from several patients simultaneously and less instrument time per patient is required.

Flexible and independent
Sampling takes places independently from the instrument. Exhaled breath is filled into a Mylar bag under defined conditions and can subsequently be analyzed on any analytical instrument.

Application range: cooperative patients
Exp. flow control: 50 ml/s at 15 to 20 cm H2O
Insp. NO conc.: <5ppb

 ECO MEDICS reserves the right to change the specifications without notice.


  • Children and adult application
  • Supports single breath technique
  • Independent testing from NO analyzer
  • NO free air generation from ambient air
  • Integrated adaptive flow control and pressure gauge

Your Advantage

  • Collection at sites remote from the analyzer (hospital ward, clinic, workplace, school, and remote laboratory)
  • More efficient use of the existing ANALYZER CLD 88 sp
  • Collection from several patients simultaneously and less analyzer time per patient is required



  1. ATS/ERS Recommendations for Standardized Procedures for the Online and Offline Measurement of Exhaled Lower Respiratory Nitric Oxide and Nasal Nitric Oxide, 2005. Am J Respir Crit Care Med 171, 912–930 (2005).
  2. Bodini, A., Pijnenburg, M. W. H., Boner, A. L. & de Jongste, J. C. Exhaled nitric oxide in mylar balloons: influence of storage time, humidity and temperature. Mediators Inflamm. 12, 47–49 (2003).
  3. Linn, W. S. et al. Relationships of online exhaled, offline exhaled, and ambient nitric oxide in an epidemiologic survey of schoolchildren. Journal of Exposure Science & Environmental Epidemiology 19, 674–681 (2009).
  4. Yoda, Y., Otani, N., Hasunuma, H., Kanegae, H. & Shima, M. Storage conditions for stability of offline measurement of fractional exhaled nitric oxide after collection for epidemiologic research. BMC Pulm Med 12, 68 (2012).

FeNO Testing

Exhaled nitric oxide analysis for asthma management and PCD screening in cooperative and non-cooperative patients

ANALYZER CLD 88 sp – FeNO analysis by single and multiple breath testing; bronchial, alveolar and nasal FeNO

Pulmonary Function Testing

Detection and monitoring of ventilation inhomogeneity and small airway diseases such as asthma, cystic fibrosis and COPD

EXHALYZER D – Nitrogen washout by single breath or multiple breath (SBW or MBW), breathing pattern (TBFVL), FRC, LCI, moment ratios and slope analysis

Infant Pulmonary Function Testing

Suitable for cooperative and non-cooperative patients from infants >3kg body weight to adults

EXHALYZER D – Breathing pattern (TBFVL), FRC, LCI and SOT analysis for patients > 3 kg body weight

Liquid NO analysis

Nitric oxide analyzer for liquid samples from biomedical or pharmaceutical applications

ANALYZER CLD 88 – Liquid NO detection in combination with liquid purge vessel and chromatographic software